How Accurate Is Genetic Testing, And When Should You Consider It?

April 30, 2020 / Dr. Aaron G. Margulies / Genetic testing, Breast Cancer Research

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Genetic testing is an increasingly important topic in both breast cancer research as well as the prevention and treatment of the disease. The most important and well-known inherited genetic factors that influence your risk for breast cancer are mutations in the genes called BRCA1 and BRCA2.

BRCA cancer risks, BRCA genetic testing, HBOC

Our 6 Most Inspiring Takeaways From The School of Breast Oncology

December 5, 2019 / Dr. Aaron G. Margulies / Breast Cancer Research, Genetic testing

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The world of breast cancer research and treatment is always changing, so staying on top of the most up-to-date advances in providing patient care simply must be a continual pursuit.

For that reason, Dr. Aaron Margulies, Breast Surgical Oncologist, and his wife Imelda Margulies, FNP and Director of Clinical Genetics Services, recently attended and received diplomas from the School of Breast Oncology in Atlanta, Georgia.

How The Expanded Guidelines For Genetic Testing May Affect You—And Your Children

November 6, 2019 / Dr. Aaron G. Margulies / Genetic testing, Breast Cancer Research

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Medical guidelines about who should be advised to have genetic testing for hereditary breast or ovarian cancer have long been difficult to pin down. For example, most recently, the American Society of Breast Surgeons released updated guidelines advising that testing should be made available to all patients with a personal history of breast cancer.

First Immunotherapy Regimen for Triple-Negative Breast Cancer Approved By FDA

June 12, 2019 / Dr. Aaron G. Margulies / Breast Cancer Treatment, Breast Cancer Research

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The U.S. Food and Drug Administration has recently granted its first approval to an immunotherapy regimen for Triple Negative Breast Cancer, which is significant because Triple Negative Breast Cancer tumors are generally high-grade, aggressive, and typically more likely to spread and recur.

Low Dose Tamoxifen Reduces Risk Of Recurrence For Some Breast Cancers

May 3, 2019 / Dr. Aaron G. Margulies / Breast Cancer Treatment, Breast Cancer Research

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For women diagnosed with hormone-receptor-positive DCIS, a new study has determined that low dose Tamoxifen after surgery reduced the risk of the disease coming back. Low dose tamoxifen also reduced the risk of developing a new invasive breast cancer.

Can Some Types Of Breast Cancer Be Cured Without Surgery?

April 4, 2019 / Dr. Aaron G. Margulies / Breast Cancer Surgery, Breast Cancer Research

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Many patients assume that surgery is the first step towards treatment, and this is true in that doctors do typically recommend surgery to remove a tumor for both early-stage invasive breast cancer and DCIS.

New Research Links BRCA2 Breast Cancer Gene With Pancreatic Cancer Risk

March 25, 2019 / Dr. Aaron G. Margulies / Breast Cancer Research, Breast Cancer Treatment

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According to the American Cancer Society, pancreatic cancer is currently the third leading cause of cancer-related deaths in the U.S., and rates are rising faster than any other cancer in the country. Researchers predict it will become the second deadliest cancer in the U.S. by 2030, second only to lung cancer.

More Hope For PARP Inhibitors In Treating Breast Cancer

March 8, 2019 / Dr. Aaron G. Margulies / Breast Cancer Research

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We hosted a dinner on PARP Inhibitors recently. PARP Inhibitors are a class of medications that may have benefits in Triple Negative and other Breast Cancers in women with a BRCA mutation. Homologous Recombination Deficiencies are associated with several cancers, including breast cancer, and can be identified in breast cancer tissue itself. Tumors with a homologous recombination deficiency (including BRCA mutations) are described as HRD-positive.

Concerns About Genetic Testing Kits For Detecting Breast Cancer Genes

November 21, 2018 / Dr. Aaron G. Margulies / Genetic testing, Breast Cancer Diagnosis, Breast Cancer Research, Breast Cancer Treatment

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You’ve most likely seen the ads on TV for home-kits like 23andMe that can tell you about your ancestry through saliva testing. 23andMe is now offering the ability to give you FDA approved health reports as well, and people are curious if these reports can determine if they carry the BRCA1 and BRCA2 genes, which increase the risk of breast and ovarian cancer.

Why You Need To Know About HBOC Week and Previvor Day

September 24, 2018 / Dr. Aaron G. Margulies / Breast Cancer Diagnosis, Breast Cancer Research

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The last week of September is National Hereditary Breast and Ovarian Cancer (HBOC) Week, and October 3rd is National Previvor Day. These are both important events to raise awareness about hereditary cancer and the importance of BRCA gene testing. Millions of people carry an inherited BRCA gene mutation or have a family history of cancer, but many remain unaware of their risk. National HBOC Week and Previvor Day aim to change that.